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Effect of a Very-Low-Calorie Ketogenic Diet on Circulating Myokine Levels Compared with the Effect of Bariatric Surgery or a Low-Calorie Diet in Patients with Obesity

dc.contributor.authorSajoux, Ignacio
dc.contributor.authorLorenzo, Paula M.
dc.contributor.authorGomez-Arbelaez, Diego
dc.contributor.authorZulet, M. Angeles
dc.contributor.authorAbete, Itziar
dc.contributor.authorCastro, Ana I.
dc.contributor.authorBaltar, Javier
dc.contributor.authorPortillo, María P.
dc.contributor.authorTinahones, Francisco J.
dc.contributor.authorMartinez, J. Alfredo
dc.contributor.authorCrujeiras, Ana B.
dc.contributor.authorCasanueva, Felipe F.
dc.contributor.researchgroupMasiraspa
dc.date.accessioned2022-05-06T16:38:17Z
dc.date.available2022-05-06T16:38:17Z
dc.date.issued2019-10-04
dc.descriptionDigitalspa
dc.description.abstractThe preservation of muscle mass and muscle function after weight loss therapy is currently a considerable challenge in the fight against obesity. Muscle mass secretes proteins called myokines that have relevant functions in the regulation of metabolism and health. This study was aimed to evaluate whether a very low-calorie ketogenic (VLCK) diet may modulate myokine levels, in addition to changes in body composition, compared to a standard, balanced low-calorie (LC) diet or bariatric surgery in patients with obesity. Body composition, ketosis, insulin sensitivity and myokines were evaluated in 79 patients with overweight/obesity after a therapy to lose weight with a VLCK diet, a LC diet or bariatric surgery. The follow-up was 6 months. The weight loss therapies induced changes in myokine levels in association with changes in body composition and biochemical parameters. The effects on circulating myokine levels compared to those at baseline were stronger after the VLCK diet than LC diet or bariatric surgery. Differences reached statistical significance for IL-8, MMP2 and irisin. In conclusion, nutritional interventions or bariatric surgery to lose weight induces changes in circulating myokine levels, being this effect potentially most notable after following a VLCK diet.spa
dc.description.researchareaCiencias Médicas y de la Saludspa
dc.format.extent17 pspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.doi10.3390/nu11102368
dc.identifier.eissn2072-664spa
dc.identifier.issn2072-6643spa
dc.identifier.urihttps://repositorio.udes.edu.co/handle/001/6723
dc.language.isoengspa
dc.publisher.placeSuizaspa
dc.relation.citationendpage17spa
dc.relation.citationissue10spa
dc.relation.citationstartpage1spa
dc.relation.citationvolume11spa
dc.relation.citesSajoux, I.; Lorenzo, P.M.; Gomez-Arbelaez, D.; Zulet, M.A.; Abete, I.; Castro, A.I.; Baltar, J.; Portillo, M.P.; Tinahones, F.J.; Martinez, J.A.; Crujeiras, A.B.; Casanueva, F.F. Effect of a Very-Low-Calorie Ketogenic Diet on Circulating Myokine Levels Compared with the Effect of Bariatric Surgery or a Low-Calorie Diet in Patients with Obesity. Nutrients 2019, 11, 2368. https://doi.org/10.3390/nu11102368
dc.relation.indexedScopusspa
dc.relation.ispartofjournalNutrientsspa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.creativecommonsAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)spa
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/spa
dc.sourcehttps://www.mdpi.com/2072-6643/11/10/2368spa
dc.subject.proposalBariatric surgeryeng
dc.subject.proposalBody compositioneng
dc.subject.proposalFat free masseng
dc.subject.proposalKetogenic dieteng
dc.subject.proposalObesityeng
dc.subject.proposalPnK methodeng
dc.subject.proposalProtein dieteng
dc.subject.proposalLow-calorie dieteng
dc.subject.proposalVery low-energy dieteng
dc.titleEffect of a Very-Low-Calorie Ketogenic Diet on Circulating Myokine Levels Compared with the Effect of Bariatric Surgery or a Low-Calorie Diet in Patients with Obesityspa
dc.typeArtículo de revistaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.type.contentTextspa
dc.type.driverinfo:eu-repo/semantics/articlespa
dc.type.redcolhttp://purl.org/redcol/resource_type/ARTspa
dc.type.versioninfo:eu-repo/semantics/publishedVersionspa
dcterms.audienceTodas las Audienciasspa
dspace.entity.typePublication
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2spa
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
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