Examinando por Autor "Sierra Castrillo, Jhoalmis."

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  • Publicación
    Acceso abierto
    Asociación de los niveles de adiponectina y del factor de necrosis tumoral alfa con albuminuria en pacientes con diabetes tipo 2
    (2017) Sierra Castrillo, Jhoalmis.; Gómez Rave, Liz J.
    Type 2 Diabetes mellitus is a metabolic chronic disease, which if it is not properly controlled produces a progressive kidney damage causing diabetc nephropathy. It is also highly associated with a chronic infammatory state, related to adipocytokines (IL-6, TNF-α, leptn, adiponectn) secreton which are involved in metabolic homeostasis and crucial in both regulatng the atherogenic process as in insulin resistance. Objectve: To relate the behavior of adiponectn and TNF-α levels with albumi- nuria in patents with type 2 diabetes mellitus. Materials and methods: The research was based on a descriptve cross-sectonal model with a study populaton composed by patents admited to University Hospital Erasmo Meoz (Cucuta, Colombia). According to previously established selecton criteria, two analysis groups were conformed; patents diagnosed with type 2 diabetes mellitus and albuminuria >30 mg/L (n = 24), and a control group without the above conditons (n = 20). Results: The results revealed that there is a positve and statstcally signifcant correlaton between TNF-α concentraton and albuminuria (p <0.03). It was observed that between TNF-α and adiponectn levels there are no apparently correlaton (p> 0.05). Conclusions: although there are no signifcant diferences between adiponectn and TNF-α levels, TNF-α could be exploited as an early markers for kidney damage or help designing of progression estmators of injury in patents with diabetes type 2.
  • Publicación
    Acceso abierto
    Eect of the addition of Moringa Oleifera to fruit drinks on clinical parameters associated with iron deciency anaemia in schoolchildren
    (2019, 2019-09-01) Martínez Marciales, Karen-Piedad; Soto, Javier-Andrés; Sierra Castrillo, Jhoalmis.; Olivieri Moncada, Jonathan-Gonzalo; Galeano Arias, Jaizul-Carolina; Gómez Rave, Lyz Jenny
    Effect of the addition of Moringa oleifera to fruit drinks on clinical parameters associated with iron deficiency anaemia in schoolchildren. Worldwide, iron deficiency anaemia (IDA) is one the most significant nutritional maladies, especially in low and middle-income countries. This is mainly due to the associated morbidity, economic implications on the health system and the welfare state. One of the most prevalent causes of IDA in children is insufficient food intake, which has an obvious connection with the social environment. The main strategy in the management of this condition is counteracting such deficiency through the improvement of nutrition and family upbringing. Aiming to explore affordable, novel and straightforward approaches to treat this nutritional condition, we developed a descriptive study associated with the incorporation of Moringa oleifera in homemade fruit beverages delivered to 32 children from low-income families, in order to assess the evolution of IDA, evaluating specific clinical parameters such as red blood cells volume, as well as hemoglobin, ferritin and serum iron levels, within a two months lapse. At the end of this period, we observed a significant statistical rise in the levels of all the assessed parameters, finding about a 1.3-fold increase in hemoglobin and ferritin levels and in red blood cells volume; serum iron was 1.1 times higher. These findings are demonstrative of the wide spectrum of the medicinal features of Moringa and establish a promising and accessible strategy easy to incorporate into the diet of families of children suffering this pathology. ALAN, 2019; 69(1): 2-11.