Examinando por Materia "δ-endotoxin"
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- PublicaciónAcceso abiertoParticipation of valine 171 in α-helix 5 of Bacillus thuringiensis Cry1Ab δ-endotoxin in translocation of toxin into Lymantria dispar midgut membranes(2010-10-01) Alzate, Oscar; Osorio, Cristina; Florez, Alvaro M.; Dean, Donald H.The Cry1Ab δ-endotoxin V171C mutant protein exhibits a 25-fold increase in toxicity against Lymantria dispar, which correlates with a faster rate of partitioning into the midgut membrane and slightly decreased protein stability. This is an insect-specific mechanism; similar results were not observed in Manduca sexta, another Cry1Ab δ-endotoxin-susceptible insect.