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The prediction of Metabolic Syndrome alterations is improved by combining waist circumference and handgrip strength measurements compared to either alone

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dc.contributor.authorLopez-Lopez, Jose
dc.contributor.authorCohen, Daniel Dylan
dc.contributor.authorNey-Salazar, Daniela
dc.contributor.authorMartinez, Daniel
dc.contributor.authorOtero, Johanna
dc.contributor.authorGomez-Arbelaez, Diego
dc.contributor.authorCamacho-Lopez, Paul Antony
dc.contributor.authorSanchez-Vallejo, Gregorio
dc.contributor.authorArcos, Edgar
dc.contributor.authorNarvaez, Claudia
dc.contributor.authorGarcia, Henry
dc.contributor.authorPerez, Maritza
dc.contributor.authorMolina, Dora I.
dc.contributor.authorCure, Carlos
dc.contributor.authorSotomayor, Aristides
dc.contributor.authorRico, Alvaro
dc.contributor.authorHernandez-Triana, Eric
dc.contributor.authorDuran Parra, Myriam
dc.contributor.authorCotes, Fresia
dc.contributor.authorLeong, Darryl P.
dc.contributor.authorRangarajan, Sumathy
dc.contributor.authorYusuf, Salim
dc.contributor.authorLopez-Jaramillo, Patricio
dc.contributor.researchgroupMasiraspa
dc.date.accessioned2022-02-17T21:42:09Z
dc.date.available2022-02-17T21:42:09Z
dc.date.issued2021-03-22
dc.descriptionDigitalspa
dc.description.abstractBackground: Adiposity is a major component of the metabolic syndrome (MetS), low muscle strength has also been identifed as a risk factor for MetS and for cardiovascular disease. We describe the prevalence of MetS and evaluate the relationship between muscle strength, anthropometric measures of adiposity, and associations with the cluster of the components of MetS, in a middle-income country. Methods: MetS was defned by the International Diabetes Federation criteria. To assess the association between anthropometric variables (waist circumference (WC), waist-to-hip ratio (W/H), body mass index (BMI)), strength (hand‑grip/kg bodyweight (HGS/BW)) and the cluster of MetS, we created a MetS score. For each alteration (high triglycer‑ides, low HDLc, dysglycemia, or high blood pressure) one point was conferred. To evaluate the association an index of fat:muscle and MetS score, participants were divided into 9 groups based on combinations of sex-specifc tertiles of WC and HGS/BW. Results: The overall prevalence of MetS in the 5,026 participants (64% women; mean age 51.2 years) was 42%. Lower HGS/BW, and higher WC, BMI, and W/H were associated with a higher MetS score. Amongst the 9 HGS/BW:WC groups, participants in the lowest tertile of HGS/BW and the highest tertile of WC had a higher MetS score (OR=4.69 in women and OR=8.25 in men;p<0.01) compared to those in the highest tertile of HGS/BW and in the lowest tertile of WC. Conclusion: WC was the principal risk factor for a high MetS score and an inverse association between HGS/BW and MetS score was found. Combining these anthropometric measures improved the prediction of metabolic alterations over either alonespa
dc.description.researchareaCiencias Médicas y de la Saludspa
dc.format.extent11 pspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.doihttps://doi.org/10.1186/s12933-021-01256-z
dc.identifier.urihttps://repositorio.udes.edu.co/handle/001/6040
dc.language.isoengspa
dc.publisherCardiovascular Diabetologyspa
dc.publisher.placeReino Unidospa
dc.relation.citationvolume20spa
dc.relation.citesLopez-Lopez, J.P., Cohen, D.D., Ney-Salazar, D. et al. The prediction of Metabolic Syndrome alterations is improved by combining waist circumference and handgrip strength measurements compared to either alone. Cardiovasc Diabetol 20, 68 (2021). https://doi.org/10.1186/s12933-021-01256-z
dc.relation.indexedScopusspa
dc.relation.ispartofjournalCardiovascular Diabetologyspa
dc.rightsCopyright © 2021, The Author(s)spa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.creativecommonsAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)spa
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/spa
dc.sourcehttps://cardiab.biomedcentral.com/articles/10.1186/s12933-021-01256-zspa
dc.titleThe prediction of Metabolic Syndrome alterations is improved by combining waist circumference and handgrip strength measurements compared to either alonespa
dc.typeArtículo de revistaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.type.contentTextspa
dc.type.driverinfo:eu-repo/semantics/articlespa
dc.type.redcolhttp://purl.org/redcol/resource_type/ARTspa
dc.type.versioninfo:eu-repo/semantics/publishedVersionspa
dcterms.audienceTodas las Audienciasspa
dspace.entity.typePublication
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2spa
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
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