Publicación:
Associations of cereal grains intake with cardiovascular disease and mortality across 21 countries in prospective urban and rural epidemiology study

Página de artículo simple
dc.contributor.authorDehghan, Mahshid
dc.contributor.authorRaj, John Michael
dc.contributor.authorThomas, Tinku
dc.contributor.authorRangarajan, Sumathy
dc.contributor.authorJenkins, David
dc.contributor.authorMony, Prem
dc.contributor.authorMohan, Viswanathan
dc.contributor.authorLear, Scott A.
dc.contributor.authorAvezum, Alvaro
dc.contributor.authorLopez-Jaramillo, Patricio
dc.contributor.authorRosengren, Annika
dc.contributor.authorLanas, Fernando
dc.contributor.authorAlHabib, Khalid F.
dc.contributor.authorDans, Antonio
dc.contributor.authorKeskinler, Mirac Vural
dc.contributor.authorPuoane, Thandi
dc.contributor.authorSoman, Biju
dc.contributor.authorWei, Li
dc.contributor.authorZatonska, Katarzyna
dc.contributor.authorDiaz, Rafael
dc.contributor.authorIsmail, Noorhassim
dc.contributor.authorChifamba, Jephat
dc.contributor.authorKelishadi, Roya
dc.contributor.authorYusufali, Afzalhussein
dc.contributor.authorKhatib, Rasha
dc.contributor.authorXiaoyun, Liu
dc.contributor.authorBo, Hu
dc.contributor.authorIqbal, Romaina
dc.contributor.authorYusuf, Rita
dc.contributor.authorYeates, Karen
dc.contributor.authorTeo, Koon
dc.contributor.authorYusuf, Salim
dc.contributor.researchgroupMasiraspa
dc.date.accessioned2022-02-17T15:58:44Z
dc.date.available2022-02-17T15:58:44Z
dc.date.issued2021-02-03
dc.descriptionDigitalspa
dc.description.abstractObjective. To evaluate the association between intakes of refined grains, whole grains, and white rice with cardiovascular disease, total mortality, blood lipids, and blood pressure in the Prospective Urban and Rural Epidemiology (PURE) study. Design. Prospective cohort study. Setting PURE study in 21 countries. Participants 148858 participants with median follow-up of 9.5 years. Exposures Country specific validated food frequency questionnaires were used to assess intakes of refined grains, whole grains, and white rice. Main outcome measure Composite of mortality or major cardiovascular events (defined as death from cardiovascular causes, nonfatal myocardial infarction, stroke, or heart failure). Hazard ratios were estimated for associations of grain intakes with mortality, major cardiovascular events, and their composite by using multivariable Cox frailty models with random intercepts to account for clustering by centre. Results Analyses were based on 137130 participants after exclusion of those with baseline cardiovascular disease. During follow-up, 9.2% (n=12668) of these participants had a composite outcome event. The highest category of intake of refined grains (≥350 g/day or about 7 servings/day) was associated with higher risk of total mortality (hazard ratio 1.27, 95% confidence interval 1.11 to 1.46; P for trend=0.004), major cardiovascular disease events (1.33, 1.16 to 1.52; P for trend<0.001), and their composite (1.28, 1.15 to 1.42; P for trend<0.001) compared with the lowest category of intake (<50 g/day). Higher intakes of refined grains were associated with higher systolic blood pressure. No significant associations were found between intakes of whole grains or white rice and health outcomes. Conclusion High intake of refined grains was associated with higher risk of mortality and major cardiovascular disease events. Globally, lower consumption of refined grains should be considered.spa
dc.description.researchareaCiencias Médicas y de la Saludspa
dc.format.extent16 pspa
dc.format.mimetypeapplication/pdfspa
dc.identifier.doihttp://dx.doi.org/10.1136/bmj.m4948
dc.identifier.urihttps://repositorio.udes.edu.co/handle/001/6031
dc.language.isoengspa
dc.publisherBMJspa
dc.publisher.placeReino Unidospa
dc.relation.citationendpage16spa
dc.relation.citationissue4948spa
dc.relation.citationstartpage1spa
dc.relation.citesBMJ 2021;372:m4948
dc.relation.indexedScopusspa
dc.relation.ispartofjournalThe BMJspa
dc.rightsCopyrights The Authors, BMJ, 2021spa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.creativecommonsAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)spa
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/spa
dc.sourcehttps://www.bmj.com/content/bmj/372/bmj.m4948.full.pdfspa
dc.titleAssociations of cereal grains intake with cardiovascular disease and mortality across 21 countries in prospective urban and rural epidemiology studyspa
dc.title.alternativeProspective cohort studyspa
dc.typeArtículo de revistaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.type.contentTextspa
dc.type.driverinfo:eu-repo/semantics/articlespa
dc.type.redcolhttp://purl.org/redcol/resource_type/ARTspa
dc.type.versioninfo:eu-repo/semantics/publishedVersionspa
dcterms.audienceTodas las Audienciasspa
dspace.entity.typePublication
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2spa
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
Archivos
Paquete original
Mostrando 1 - 1 de 1
Imagen en miniatura
Nombre:
Associations of cereal grains intake with cardiovascular disease and mortality across 21 countries in prospective urban and rural epidemiology study. Prospective cohort study.pdf
Tamaño:
239.61 KB
Formato:
Adobe Portable Document Format
Descripción:
Descargar
Paquete de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
59 B
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar
Colecciones
AGBBA. Artículos de Investigación