Publicación:
Prognostic value of grip strength : Findings from the Prospective Urban Rural Epidemiology (PURE) study

Página de artículo simple
dc.contributor.authorLeong, Darryl P.spa
dc.contributor.authorTeo, Koonspa
dc.contributor.authorRangarajan, Sumathyspa
dc.contributor.authorLopez-Jaramillo, Patriciospa
dc.contributor.authorAvezum, Alvarospa
dc.contributor.authorOrlandini, Andresspa
dc.contributor.authorSeron, Pamelaspa
dc.contributor.authorAhmed, Suad H.spa
dc.contributor.authorRosengren, Annikaspa
dc.contributor.authorKelishadi, Royaspa
dc.contributor.authorRahman, Omarspa
dc.contributor.authorSwaminathan, Sumathispa
dc.contributor.authorIqbal, Romainaspa
dc.contributor.authorGupta, Rajeevspa
dc.contributor.authorLear, Scott A.spa
dc.contributor.authorOguz, Aytekinspa
dc.contributor.authorYusoff, Khalidspa
dc.contributor.authorZatonska, Katarzynaspa
dc.contributor.authorChifamba, Jephatspa
dc.contributor.authorIgumbor, Ehimariospa
dc.contributor.authorMohan, Viswanathanspa
dc.contributor.authorAnjana, Ranjit Mohanspa
dc.contributor.authorGu, Hongqiuspa
dc.contributor.authorLi, Weispa
dc.contributor.authorYusuf, Salimspa
dc.contributor.authorThe PURE (Prospective Urban Rural Epidemiology) Study investigatorseng
dc.date.accessioned2019-08-06T16:28:00Zspa
dc.date.available2019-08-06T16:28:00Zspa
dc.date.issued2015-07spa
dc.description8 p.spa
dc.description.abstractBackground Reduced muscular strength, as measured by grip strength, has been associated with an increased risk of all-cause and cardiovascular mortality. Grip strength is appealing as a simple, quick, and inexpensive means of stratifying an individual's risk of cardiovascular death. However, the prognostic value of grip strength with respect to the number and range of populations and confounders is unknown. The aim of this study was to assess the independent prognostic importance of grip strength measurement in socioculturally and economically diverse countries. Methods The Prospective Urban-Rural Epidemiology (PURE) study is a large, longitudinal population study done in 17 countries of varying incomes and sociocultural settings. We enrolled an unbiased sample of households, which were eligible if at least one household member was aged 35–70 years and if household members intended to stay at that address for another 4 years. Participants were assessed for grip strength, measured using a Jamar dynamometer. During a median follow-up of 4·0 years (IQR 2·9–5·1), we assessed all-cause mortality, cardiovascular mortality, non-cardiovascular mortality, myocardial infarction, stroke, diabetes, cancer, pneumonia, hospital admission for pneumonia or chronic obstructive pulmonary disease (COPD), hospital admission for any respiratory disease (including COPD, asthma, tuberculosis, and pneumonia), injury due to fall, and fracture. Study outcomes were adjudicated using source documents by a local investigator, and a subset were adjudicated centrally. Findings Between January, 2003, and December, 2009, a total of 142 861 participants were enrolled in the PURE study, of whom 139 691 with known vital status were included in the analysis. During a median follow-up of 4·0 years (IQR 2·9–5·1), 3379 (2%) of 139 691 participants died. After adjustment, the association between grip strength and each outcome, with the exceptions of cancer and hospital admission due to respiratory illness, was similar across country-income strata. Grip strength was inversely associated with all-cause mortality (hazard ratio per 5 kg reduction in grip strength 1·16, 95% CI 1·13–1·20; p<0·0001), cardiovascular mortality (1·17, 1·11–1·24; p<0·0001), non-cardiovascular mortality (1·17, 1·12–1·21; p<0·0001), myocardial infarction (1·07, 1·02–1·11; p=0·002), and stroke (1·09, 1·05–1·15; p<0·0001). Grip strength was a stronger predictor of all-cause and cardiovascular mortality than systolic blood pressure. We found no significant association between grip strength and incident diabetes, risk of hospital admission for pneumonia or COPD, injury from fall, or fracture. In high-income countries, the risk of cancer and grip strength were positively associated (0·916, 0·880–0·953; p<0·0001), but this association was not found in middle-income and low-income countries. Interpretation This study suggests that measurement of grip strength is a simple, inexpensive risk-stratifying method for all-cause death, cardiovascular death, and cardiovascular disease. Further research is needed to identify determinants of muscular strength and to test whether improvement in strength reduces mortality and cardiovascular disease. Funding Full funding sources listed at end of paper (see Acknowledgments).eng
dc.format.mimetypeapplication/pdfspa
dc.identifier.doi10.1016/S0140-6736(14)62000-6spa
dc.identifier.issn0140-6736spa
dc.identifier.urihttps://repositorio.udes.edu.co/handle/001/3538spa
dc.language.isoengspa
dc.relation.ispartofThe Lanceteng
dc.rightsDerechos Reservados - The Lancet, 2015spa
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessspa
dc.rights.creativecommonsAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)spa
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/spa
dc.sourcehttps://www.sciencedirect.com/science/article/pii/S0140673614620006?via%3Dihubeng
dc.subject.proposalGripeng
dc.subject.proposalStrengtheng
dc.titlePrognostic value of grip strength : Findings from the Prospective Urban Rural Epidemiology (PURE) studyeng
dc.typeArtículo de revistaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.type.contentTextspa
dc.type.driverinfo:eu-repo/semantics/articlespa
dc.type.redcolhttp://purl.org/redcol/resource_type/ARTspa
dc.type.versioninfo:eu-repo/semantics/publishedVersionspa
dspace.entity.typePublication
oaire.accessrightshttp://purl.org/coar/access_right/c_abf2spa
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
Archivos
Paquete original
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
Prognostic value of grip strength. Findings from the Prospective Urban Rural Epidemiology (PURE) study.pdf
Tamaño:
228.15 KB
Formato:
Adobe Portable Document Format
Descripción:
Descargar
Paquete de licencias
Mostrando 1 - 1 de 1
No hay miniatura disponible
Nombre:
license.txt
Tamaño:
59 B
Formato:
Item-specific license agreed upon to submission
Descripción:
Descargar
Colecciones
AGBBA. Artículos de Investigación