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- PublicaciónRestringidoIdentificación de la actividad biológica del aceite esencial l. Alba en los diferentes sectores de la industria, mediante revisión sistemática durante el periodo de 1990 a 2018(Valledupar : Universidad de Santander, 2019, 2019-06-17) Daza Padilla, Angélica Julieth; Tofiño Rivera, Adriana Patricia; Pedraza Claros, BertildaThe Lippia alba, is an aromatic plant, commonly known as prontoalivio in Colombia, of great interest in the national and international market for its various uses especially as an essential oil. In order to identify the perspectives of application of essential oils (AE) of Lippia alba (Mill.) In the productive sectors of the Cesar department, an exploratory review of its registered biological activity was carried out from 1990 to October 2018. The methodology included the search of literature in the EBSCO, Embase, Pubmed, Scopus, Scielo and Lilacs databases. of which was obtained as a result that among the most outstanding researchers are: Bernardo Baldisserotto as the most prolific author with 11 publications, the federal university of Santa Maria stood out as the most relevant institution in number of publications (21), followed by the industrial university of Santander (9), the university of Cartagena (7) and the federal university of Ceará (6), countries such as Brazil (60.5%), Colombia (25.2%) and India (6.2%); They stood out for their research linked to the biomedical sector (46.2%) and industrial (37.3%) mainly; in which they used microorganisms, fish, arthropods, small mammals, and cell lines fundamentally, evaluated by the contact method and with positive results in oils extracted by hydrodistillation (55.3%) and steam distillation (18, 4%) as the most frequent techniques. The biological activity of the EA was associated with Carvona (30.2%) and linalool (23.6%), in relation to its antibacterial, antifungal, cytotoxic, antioxidant and sedative effects, among others. E. coli was identified as a microorganism highly sensitive to EA of L. alba. The biotechnological articulation of AE of L. alba suggests research focused on the fishing, agrifood and public health industries.